Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116085
MIM: 607096
HGNC: 17989
Ensembl: ENSG00000197891
Variants:
dbSNP: 116085
ClinVar: 116085
TCGA: ENSG00000197891
COSMIC: SLC22A12
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164749431 | gemtuzumab ozogamicin | Chemical | ClinicalAnnotation | associated | PD | 22584460 | |
| PA444760 | Leukemia, Myeloid, Acute | Disease | ClinicalAnnotation | associated | PD | 22584460 | |
| PA449177 | cytarabine | Chemical | ClinicalAnnotation | associated | PD | 22584460 | |
| PA449655 | fludarabine | Chemical | ClinicalAnnotation | associated | PD | 22584460 | |
| PA449961 | idarubicin | Chemical | ClinicalAnnotation | associated | PD | 22584460 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37176161 | 2023 | Pathogenic Variants of SLC22A12 (URAT1) and SLC2A9 (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of SLC2A9 Variant c.374C>T; p.(T125M). | 2 |
| 37761963 | 2023 | New SLC22A12 (URAT1) Variant Associated with Renal Hypouricemia Identified by Whole-Exome Sequencing Analysis and Bioinformatics Predictions. | 0 |
| 37176161 | 2023 | Pathogenic Variants of SLC22A12 (URAT1) and SLC2A9 (GLUT9) in Spanish Patients with Renal Hypouricemia: Founder Effect of SLC2A9 Variant c.374C>T; p.(T125M). | 2 |
| 37761963 | 2023 | New SLC22A12 (URAT1) Variant Associated with Renal Hypouricemia Identified by Whole-Exome Sequencing Analysis and Bioinformatics Predictions. | 0 |
| 34255816 | 2022 | Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of URAT1/SLC22A12 gene. | 6 |
| 34255816 | 2022 | Genetic epidemiological analysis of hypouricaemia from 4993 Japanese on non-functional variants of URAT1/SLC22A12 gene. | 6 |
| 33368618 | 2021 | 27-Hydroxycholesterol regulates human SLC22A12 gene expression through estrogen receptor action. | 9 |
| 33821957 | 2021 | Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12. | 7 |
| 34498315 | 2021 | The impact of an URAT1 polymorphism on the losartan treatment of hypertension and hyperuricemia. | 3 |
| 34631016 | 2021 | Polymorphisms of the genes ABCG2, SLC22A12 and XDH and their relation with hyperuricemia and hypercholesterolemia in Mexican young adults. | 1 |
| 33368618 | 2021 | 27-Hydroxycholesterol regulates human SLC22A12 gene expression through estrogen receptor action. | 9 |
| 33821957 | 2021 | Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12. | 7 |
| 34498315 | 2021 | The impact of an URAT1 polymorphism on the losartan treatment of hypertension and hyperuricemia. | 3 |
| 34631016 | 2021 | Polymorphisms of the genes ABCG2, SLC22A12 and XDH and their relation with hyperuricemia and hypercholesterolemia in Mexican young adults. | 1 |
| 31841133 | 2020 | Refining genome-wide associated loci for serum uric acid in individuals with African ancestry. | 5 |
Citation
Dessen P
SLC22A12 (solute carrier family 22 member 12)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73316/slc22a12-(solute-carrier-family-22-member-12)
