SLC25A51 (solute carrier family 25 member 51)

2014-11-01  

Identity

HGNC
SLC25A51
LOCATION
9p13.2
LOCUSID
92014
ALIAS
CG7943,MCART1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92014
HGNC: 23323
Ensembl: ENSG00000122696

Variants:

dbSNP: 92014
ClinVar: 92014
TCGA: ENSG00000122696
COSMIC: SLC25A51

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122696ENST00000242275Q9H1U9
ENSG00000122696ENST00000377716Q9H1U9

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
383547402024SLC25A51 decouples the mitochondrial NAD(+)/NADH ratio to control proliferation of AML cells.0
383547402024SLC25A51 decouples the mitochondrial NAD(+)/NADH ratio to control proliferation of AML cells.0
374199862023SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis.5
375750342023Dynamics of SLC25A51 reveal preference for oxidized NAD(+) and substrate led transport.4
375876952023Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.3
381084692023Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51.0
374199862023SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis.5
375750342023Dynamics of SLC25A51 reveal preference for oxidized NAD(+) and substrate led transport.4
375876952023Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.3
381084692023Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51.0
335833032021Differential levels of CHMP2B, LLPH, and SLC25A51 proteins in secondary renal amyloidosis.0
341985032021Welcome to the Family: Identification of the NAD(+) Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25.13
335833032021Differential levels of CHMP2B, LLPH, and SLC25A51 proteins in secondary renal amyloidosis.0
341985032021Welcome to the Family: Identification of the NAD(+) Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25.13
329061422020SLC25A51 is a mammalian mitochondrial NAD(+) transporter.117

Citation

Dessen P

SLC25A51 (solute carrier family 25 member 51)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73367/slc25a51-(solute-carrier-family-25-member-51)