Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 115019
MIM: 608481
HGNC: 14469
Ensembl: ENSG00000174502
Variants:
dbSNP: 115019
ClinVar: 115019
TCGA: ENSG00000174502
COSMIC: SLC26A9
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174502 | ENST00000340781 | Q7LBE3 |
| ENSG00000174502 | ENST00000367134 | Q7LBE3 |
| ENSG00000174502 | ENST00000367135 | Q7LBE3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA165950341 | ivacaftor | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443829 | Cystic Fibrosis | Disease | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38773769 | 2024 | The role of the STAS domain in SLC26A9 for chloride ion transporter function. | 0 |
| 38773769 | 2024 | The role of the STAS domain in SLC26A9 for chloride ion transporter function. | 0 |
| 37068695 | 2023 | Identification of single nucleotide variants in SLC26A9 gene in patients with cystic fibrosis (p.Phe508del homozygous) and its association to Orkambi® (Lumacaftor and Ivacaftor) response in vitro. | 2 |
| 37686084 | 2023 | Pathogenic Relationships in Cystic Fibrosis and Renal Diseases: CFTR, SLC26A9 and Anoctamins. | 2 |
| 37068695 | 2023 | Identification of single nucleotide variants in SLC26A9 gene in patients with cystic fibrosis (p.Phe508del homozygous) and its association to Orkambi® (Lumacaftor and Ivacaftor) response in vitro. | 2 |
| 37686084 | 2023 | Pathogenic Relationships in Cystic Fibrosis and Renal Diseases: CFTR, SLC26A9 and Anoctamins. | 2 |
| 35328418 | 2022 | Expression of SLC26A9 in Airways and Its Potential Role in Asthma. | 7 |
| 35426084 | 2022 | SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans. | 7 |
| 35328418 | 2022 | Expression of SLC26A9 in Airways and Its Potential Role in Asthma. | 7 |
| 35426084 | 2022 | SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans. | 7 |
| 33674211 | 2021 | SLC26A9 SNP rs7512462 is not associated with lung disease severity or lung function response to ivacaftor in cystic fibrosis patients with G551D-CFTR. | 7 |
| 34821356 | 2021 | SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain. | 3 |
| 34884866 | 2021 | Synergy in Cystic Fibrosis Therapies: Targeting SLC26A9. | 9 |
| 34944008 | 2021 | Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid-Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario. | 5 |
| 33674211 | 2021 | SLC26A9 SNP rs7512462 is not associated with lung disease severity or lung function response to ivacaftor in cystic fibrosis patients with G551D-CFTR. | 7 |
Citation
Dessen P
SLC26A9 (solute carrier family 26 member 9)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73377/slc26a9-(solute-carrier-family-26-member-9)
