Identity
HGNC
LOCATION
19q13.43
LOCUSID
ALIAS
ACSB,ACSVL6,BACS,BAL,FACVL3,FATP-5,FATP5,VLACSR,VLCS-H2,VLCSH2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10998
MIM: 603314
HGNC: 10999
Ensembl: ENSG00000083807
Variants:
dbSNP: 10998
ClinVar: 10998
TCGA: ENSG00000083807
COSMIC: SLC27A5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000083807 | ENST00000263093 | Q9Y2P5 |
| ENSG00000083807 | ENST00000594786 | M0R075 |
| ENSG00000083807 | ENST00000595851 | M0R075 |
| ENSG00000083807 | ENST00000601355 | Q9Y2P5 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37957540 | 2024 | Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid. | 3 |
| 38059827 | 2024 | Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre-mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis. | 1 |
| 37957540 | 2024 | Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid. | 3 |
| 38059827 | 2024 | Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre-mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis. | 1 |
| 36635256 | 2023 | SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase. | 19 |
| 38157255 | 2023 | Copper metabolism-related risk score identifies hepatocellular carcinoma subtypes and SLC27A5 as a potential regulator of cuproptosis. | 1 |
| 36635256 | 2023 | SLC27A5 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by downregulating glutathione reductase. | 19 |
| 38157255 | 2023 | Copper metabolism-related risk score identifies hepatocellular carcinoma subtypes and SLC27A5 as a potential regulator of cuproptosis. | 1 |
| 31367013 | 2020 | SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC. | 54 |
| 31602526 | 2020 | Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients. | 26 |
| 31367013 | 2020 | SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC. | 54 |
| 31602526 | 2020 | Hepatic FATP5 expression is associated with histological progression and loss of hepatic fat in NAFLD patients. | 26 |
| 23415802 | 2013 | Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. | 30 |
| 23415802 | 2013 | Genetic defects in bile acid conjugation cause fat-soluble vitamin deficiency. | 30 |
| 22089923 | 2012 | Bile acid-CoA ligase deficiency--a new inborn error of bile acid metabolism. | 17 |
Citation
Dessen P
SLC27A5 (solute carrier family 27 member 5)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73380/slc27a5-(solute-carrier-family-27-member-5)
