Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9153
MIM: 606208
HGNC: 11002
Ensembl: ENSG00000137860
Variants:
dbSNP: 9153
ClinVar: 9153
TCGA: ENSG00000137860
COSMIC: SLC28A2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137860 | ENST00000347644 | O43868 |
| ENSG00000137860 | ENST00000559924 | H0YNK4 |
| ENSG00000137860 | ENST00000560438 | H0YNM6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA162263533 | nephrotoxicity | Disease | ClinicalAnnotation | associated | PD | 31619748 | |
| PA164784024 | peginterferon alfa-2b | Chemical | ClinicalAnnotation | associated | PD | 26071337 | |
| PA165948902 | boceprevir | Chemical | MultilinkAnnotation | associated | 25836019 | ||
| PA166201941 | tenofovir disoproxil fumarate | Chemical | ClinicalAnnotation | associated | PD | 31619748 | |
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 18538445 | |
| PA444445 | Hepatitis C | Disease | ClinicalAnnotation | associated | PD | 26071337 | |
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | 18538445, 20665488 | |
| PA447230 | HIV Infections | Disease | ClinicalAnnotation | associated | PD | 31619748 | |
| PA449748 | gemcitabine | Chemical | ClinicalAnnotation | associated | PD | 18538445, 20665488 | |
| PA451159 | protease inhibitors | Chemical | ClinicalAnnotation | associated | PD | 26071337 | |
| PA451241 | ribavirin | Chemical | ClinicalAnnotation | associated | PD | 26071337 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33910126 | 2021 | Characterization of deoxyribonucleoside transport mediated by concentrative nucleoside transporters. | 5 |
| 33910126 | 2021 | Characterization of deoxyribonucleoside transport mediated by concentrative nucleoside transporters. | 5 |
| 30679935 | 2019 | Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese. | 4 |
| 30679935 | 2019 | Common variants in the SLC28A2 gene are associated with serum uric acid level and hyperuricemia and gout in Han Chinese. | 4 |
| 28385889 | 2017 | Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance. | 7 |
| 28385889 | 2017 | Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance. | 7 |
| 23195617 | 2013 | Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. | 14 |
| 23195617 | 2013 | Impact of genetic SLC28 transporter and ITPA variants on ribavirin serum level, hemoglobin drop and therapeutic response in patients with HCV infection. | 14 |
| 23149444 | 2012 | Negative predictive value of IL28B, SLC28A2, and CYP27B1 SNPs and low RBV plasma exposure for therapeutic response to PEG/IFN-RBV treatment. | 2 |
| 23149444 | 2012 | Negative predictive value of IL28B, SLC28A2, and CYP27B1 SNPs and low RBV plasma exposure for therapeutic response to PEG/IFN-RBV treatment. | 2 |
| 20028759 | 2010 | Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20392501 | 2010 | Contribution of adenosine related genes to the risk of depression with disturbed sleep. | 23 |
| 20506327 | 2010 | Link between high-affinity adenosine concentrative nucleoside transporter-2 (CNT2) and energy metabolism in intestinal and liver parenchymal cells. | 8 |
| 20028759 | 2010 | Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. | 37 |
Citation
Dessen P
SLC28A2 (solute carrier family 28 member 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73381/slc28a2-(solute-carrier-family-28-member-2)
