Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 169026
MIM: 611145
HGNC: 20303
Ensembl: ENSG00000164756
Variants:
dbSNP: 169026
ClinVar: 169026
TCGA: ENSG00000164756
COSMIC: SLC30A8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164744571 | insulin recombinant | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443890 | Diabetes Mellitus, Type 2 | Disease | ClinicalAnnotation, MultilinkAnnotation | associated | PD | 20809084, 24471563 | |
| PA451234 | repaglinide | Chemical | ClinicalAnnotation | associated | PD | 20809084 | |
| PA451961 | zinc acetate | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38661000 | 2024 | Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function. | 1 |
| 38985991 | 2024 | Electrophysiological Characterization of Inducible Pluripotent Stem Cell-Derived Human β-Like Cells and an SLC30A8 Disease Model. | 0 |
| 38661000 | 2024 | Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function. | 1 |
| 38985991 | 2024 | Electrophysiological Characterization of Inducible Pluripotent Stem Cell-Derived Human β-Like Cells and an SLC30A8 Disease Model. | 0 |
| 35793043 | 2023 | Relationship Between the Single Nucleotide Polymorphism rs11558471 in the SLC30A8/ZnT8 Gene and Cardiometabolic Markers in Postmenopausal Women. | 0 |
| 36827808 | 2023 | Effects of a genetic variant rs13266634 in the zinc transporter 8 gene (SLC30A8) on insulin and lipid levels before and after a high-fat mixed macronutrient tolerance test in U.S. adults. | 0 |
| 36980244 | 2023 | ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition. | 3 |
| 37103601 | 2023 | Association of HHEX and SLC30A8 Gene Polymorphisms with Gestational Diabetes Mellitus Susceptibility: A Meta-analysis. | 4 |
| 37324267 | 2023 | Association of solute carrier family 30 A8 zinc transporter gene variations with gestational diabetes mellitus risk in a Chinese population. | 3 |
| 37707576 | 2023 | Zinc intake, SLC30A8 rs3802177 polymorphism, and colorectal cancer risk in a Korean population: a case-control study. | 0 |
| 35793043 | 2023 | Relationship Between the Single Nucleotide Polymorphism rs11558471 in the SLC30A8/ZnT8 Gene and Cardiometabolic Markers in Postmenopausal Women. | 0 |
| 36827808 | 2023 | Effects of a genetic variant rs13266634 in the zinc transporter 8 gene (SLC30A8) on insulin and lipid levels before and after a high-fat mixed macronutrient tolerance test in U.S. adults. | 0 |
| 36980244 | 2023 | ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition. | 3 |
| 37103601 | 2023 | Association of HHEX and SLC30A8 Gene Polymorphisms with Gestational Diabetes Mellitus Susceptibility: A Meta-analysis. | 4 |
| 37324267 | 2023 | Association of solute carrier family 30 A8 zinc transporter gene variations with gestational diabetes mellitus risk in a Chinese population. | 3 |
Citation
Dessen P
SLC30A8 (solute carrier family 30 member 8)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73392/slc30a8-(solute-carrier-family-30-member-8)
