SLC34A1 (solute carrier family 34 member 1)

2014-11-01  

Identity

HGNC
LOCATION
5q35.3
LOCUSID
ALIAS
FRTS2,HCINF2,NAPI-3,NPHLOP1,NPT2,NPTIIa,SLC11,SLC17A2

Other Information

Locus ID:

NCBI: 6569
MIM: 182309
HGNC: 11019
Ensembl: ENSG00000131183

Variants:

dbSNP: 6569
ClinVar: 6569
TCGA: ENSG00000131183
COSMIC: SLC34A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131183ENST00000324417Q06495
ENSG00000131183ENST00000324417A0A024R7R9
ENSG00000131183ENST00000504577D6RCE5
ENSG00000131183ENST00000512593Q06495

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Sodium-coupled phosphate cotransportersREACTOMER-HSA-427652
Type II Na+/Pi cotransportersREACTOMER-HSA-427589
Surfactant metabolismREACTOMER-HSA-5683826

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385042422024Biallelic and monoallelic pathogenic variants in CYP24A1 and SLC34A1 genes cause idiopathic infantile hypercalcemia.0
385042422024Biallelic and monoallelic pathogenic variants in CYP24A1 and SLC34A1 genes cause idiopathic infantile hypercalcemia.0
367629432023High frequency of heterozygous rare variants of the SLC34A1 and SLC9A3R1 genes in patients with atypical femur fracture.0
367629432023High frequency of heterozygous rare variants of the SLC34A1 and SLC9A3R1 genes in patients with atypical femur fracture.0
354140992022The human pathogenic 91del7 mutation in SLC34A1 has no effect in mineral homeostasis in mice.1
354140992022The human pathogenic 91del7 mutation in SLC34A1 has no effect in mineral homeostasis in mice.1
328580212021Nephrolithiasis from an Unexpected Cause: Phosphaturia.1
330996302021Long-term outcome of the survivors of infantile hypercalcaemia with CYP24A1 and SLC34A1 mutations.6
334993842021Noncanonical Sequences Involving NHERF1 Interaction with NPT2A Govern Hormone-Regulated Phosphate Transport: Binding Outside the Box.5
335167862021Analysis of vitamin D(3) metabolites in survivors of infantile idiopathic hypercalcemia caused by CYP24A1 mutation or SLC34A1 mutation.2
343204952021CYP24A1 and SLC34A1 Pathogenic Variants Are Uncommon in a Canadian Cohort of Children with Hypercalcemia or Hypercalciuria.1
328580212021Nephrolithiasis from an Unexpected Cause: Phosphaturia.1
330996302021Long-term outcome of the survivors of infantile hypercalcaemia with CYP24A1 and SLC34A1 mutations.6
334993842021Noncanonical Sequences Involving NHERF1 Interaction with NPT2A Govern Hormone-Regulated Phosphate Transport: Binding Outside the Box.5
335167862021Analysis of vitamin D(3) metabolites in survivors of infantile idiopathic hypercalcemia caused by CYP24A1 mutation or SLC34A1 mutation.2

Citation

Dessen P

SLC34A1 (solute carrier family 34 member 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73395/slc34a1-(solute-carrier-family-34-member-1)