SLC35A2 (solute carrier family 35 member A2)

2014-11-01  

Identity

HGNC
LOCATION
Xp11.23
LOCUSID
ALIAS
CDG2M,CDGX,UDP-Gal-Tr,UGALT,UGAT,UGT,UGT1,UGT2,UGTL
FUSION GENES

Other Information

Locus ID:

NCBI: 7355
MIM: 314375
HGNC: 11022
Ensembl: ENSG00000102100

Variants:

dbSNP: 7355
ClinVar: 7355
TCGA: ENSG00000102100
COSMIC: SLC35A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102100ENST00000247138P78381
ENSG00000102100ENST00000376512A6NGW4
ENSG00000102100ENST00000376515A6NKM8
ENSG00000102100ENST00000376521P78381
ENSG00000102100ENST00000376529A6NFI1
ENSG00000102100ENST00000413561A0A0X1KG77
ENSG00000102100ENST00000445167P78381
ENSG00000102100ENST00000446885C9JCV5
ENSG00000102100ENST00000452555P78381
ENSG00000102100ENST00000616181B4DE15
ENSG00000102100ENST00000634461A0A0U1RRB4
ENSG00000102100ENST00000634665A0A0U1RR61
ENSG00000102100ENST00000635015B4DSH7
ENSG00000102100ENST00000635238A0A0U1RRG4
ENSG00000102100ENST00000635285P78381
ENSG00000102100ENST00000635460A0A0U1RR48
ENSG00000102100ENST00000635589P78381
ENSG00000102100ENST00000635628A0A0U1RRN1

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of vitamins, nucleosides, and related moleculesREACTOMER-HSA-425397
Transport of nucleotide sugarsREACTOMER-HSA-727802

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381433142024SLC35A2 expression drives breast cancer progression via ERK pathway activation.1
381433142024SLC35A2 expression drives breast cancer progression via ERK pathway activation.1
363072172023Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the SLC35A2 Gene.7
364545142023Nucleotide sugar transporter SLC35A2 is involved in promoting hepatocellular carcinoma metastasis by regulating cellular glycosylation.6
369337712023SLC35A2 deficiency reduces protein levels of core 1 β-1,3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular localization.0
377391372023SLC35A2 somatic variants in drug resistant epilepsy: FCD and MOGHE.0
363072172023Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the SLC35A2 Gene.7
364545142023Nucleotide sugar transporter SLC35A2 is involved in promoting hepatocellular carcinoma metastasis by regulating cellular glycosylation.6
369337712023SLC35A2 deficiency reduces protein levels of core 1 β-1,3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular localization.0
377391372023SLC35A2 somatic variants in drug resistant epilepsy: FCD and MOGHE.0
334078962021Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE).32
341616962021SLC35A2-CDG: novel variants with two ends of the spectrum.0
343847822021A three-pocket model for substrate coordination and selectivity by the nucleotide sugar transporters SLC35A1 and SLC35A2.2
334078962021Frequent SLC35A2 brain mosaicism in mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE).32
341616962021SLC35A2-CDG: novel variants with two ends of the spectrum.0

Citation

Dessen P

SLC35A2 (solute carrier family 35 member A2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73398/slc35a2-(solute-carrier-family-35-member-a2)