SLC35A3 (solute carrier family 35 member A3)

2014-11-01  

Identity

HGNC
LOCATION
1p21.2
LOCUSID
ALIAS
AMRS
FUSION GENES

Other Information

Locus ID:

NCBI: 23443
MIM: 605632
HGNC: 11023
Ensembl: ENSG00000117620

Variants:

dbSNP: 23443
ClinVar: 23443
TCGA: ENSG00000117620
COSMIC: SLC35A3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117620ENST00000370153Q9Y2D2
ENSG00000117620ENST00000370155A0A1C7CYW3
ENSG00000117620ENST00000427993Q9Y2D2
ENSG00000117620ENST00000465289Q9Y2D2
ENSG00000117620ENST00000532693E9PPQ9
ENSG00000117620ENST00000533028Q9Y2D2
ENSG00000117620ENST00000638336Q9Y2D2
ENSG00000117620ENST00000638338A0A1W2PPH4
ENSG00000117620ENST00000638371A0A1W2PNY6
ENSG00000117620ENST00000638876A0A1W2PPW2
ENSG00000117620ENST00000638988A0A1W2PRN3
ENSG00000117620ENST00000639088A0A1W2PPW2
ENSG00000117620ENST00000639148A0A1W2PP85
ENSG00000117620ENST00000639221A0A1W2PQL8
ENSG00000117620ENST00000639807A0A1W2PNF0
ENSG00000117620ENST00000639994A0A1W2PQH2
ENSG00000117620ENST00000640178A0A1W2PPW2
ENSG00000117620ENST00000640360A0A1W2PPW2
ENSG00000117620ENST00000640600A0A1W2PQ60
ENSG00000117620ENST00000640715A0A1W2PSD1
ENSG00000117620ENST00000640726A0A1W2PR66
ENSG00000117620ENST00000640732A0A1W2PRT7

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of vitamins, nucleosides, and related moleculesREACTOMER-HSA-425397
Transport of nucleotide sugarsREACTOMER-HSA-727802

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381725652024Colorectal cancer with low SLC35A3 is associated with immune infiltrates and poor prognosis.0
381725652024Colorectal cancer with low SLC35A3 is associated with immune infiltrates and poor prognosis.0
334180782021Identification of HIF-dependent alternative splicing in gastrointestinal cancers and characterization of a long, coding isoform of SLC35A3.3
334180782021Identification of HIF-dependent alternative splicing in gastrointestinal cancers and characterization of a long, coding isoform of SLC35A3.3
327007712020Serum bikunin isoforms in congenital disorders of glycosylation and linkeropathies.10
329387182020Biosynthesis of GlcNAc-rich N- and O-glycans in the Golgi apparatus does not require the nucleotide sugar transporter SLC35A3.10
327007712020Serum bikunin isoforms in congenital disorders of glycosylation and linkeropathies.10
329387182020Biosynthesis of GlcNAc-rich N- and O-glycans in the Golgi apparatus does not require the nucleotide sugar transporter SLC35A3.10
283281312017Recessive mutations in SLC35A3 cause early onset epileptic encephalopathy with skeletal defects.9
287774812017A human case of SLC35A3-related skeletal dysplasia.10
283281312017Recessive mutations in SLC35A3 cause early onset epileptic encephalopathy with skeletal defects.9
287774812017A human case of SLC35A3-related skeletal dysplasia.10
259449012015UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).21
259449012015UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats).21
235834052013UDP-Gal/UDP-GlcNAc chimeric transporter complements mutation defect in mammalian cells deficient in UDP-Gal transporter.10

Citation

Dessen P

SLC35A3 (solute carrier family 35 member A3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73399/slc35a3-(solute-carrier-family-35-member-a3)