Identity
HGNC
LOCATION
12q24.13
LOCUSID
ALIAS
NCKX6,NCLX,SLC24A6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80024
MIM: 609841
HGNC: 26175
Ensembl: ENSG00000089060
Variants:
dbSNP: 80024
ClinVar: 80024
TCGA: ENSG00000089060
COSMIC: SLC8B1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34942149 | 2022 | Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic. | 6 |
| 35887296 | 2022 | Spatial and Functional Crosstalk between the Mitochondrial Na(+)-Ca(2+) Exchanger NCLX and the Sarcoplasmic Reticulum Ca(2+) Pump SERCA in Cardiomyocytes. | 5 |
| 36552754 | 2022 | CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca(2+) via Mitochondrial NCLX. | 2 |
| 34942149 | 2022 | Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic. | 6 |
| 35887296 | 2022 | Spatial and Functional Crosstalk between the Mitochondrial Na(+)-Ca(2+) Exchanger NCLX and the Sarcoplasmic Reticulum Ca(2+) Pump SERCA in Cardiomyocytes. | 5 |
| 36552754 | 2022 | CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca(2+) via Mitochondrial NCLX. | 2 |
| 34079053 | 2021 | Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation. | 20 |
| 34944520 | 2021 | Physiological and Pathophysiological Roles of Mitochondrial Na(+)-Ca(2+) Exchanger, NCLX, in Hearts. | 9 |
| 34079053 | 2021 | Aberrant activity of mitochondrial NCLX is linked to impaired synaptic transmission and is associated with mental retardation. | 20 |
| 34944520 | 2021 | Physiological and Pathophysiological Roles of Mitochondrial Na(+)-Ca(2+) Exchanger, NCLX, in Hearts. | 9 |
| 32914752 | 2020 | Dichotomous role of the human mitochondrial Na(+)/Ca2(+)/Li(+) exchanger NCLX in colorectal cancer growth and metastasis. | 27 |
| 32914752 | 2020 | Dichotomous role of the human mitochondrial Na(+)/Ca2(+)/Li(+) exchanger NCLX in colorectal cancer growth and metastasis. | 27 |
| 30658153 | 2019 | Functional properties and mode of regulation of the mitochondrial Na(+)/Ca(2+) exchanger, NCLX. | 21 |
| 30658153 | 2019 | Functional properties and mode of regulation of the mitochondrial Na(+)/Ca(2+) exchanger, NCLX. | 21 |
| 30566870 | 2018 | Allosteric Regulation of NCLX by Mitochondrial Membrane Potential Links the Metabolic State and Ca(2+) Signaling in Mitochondria. | 32 |
Citation
Dessen P
SLC8B1 (solute carrier family 8 member B1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73494/slc8b1-(solute-carrier-family-8-member-b1)
