Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6553
MIM: 600477
HGNC: 11078
Ensembl: ENSG00000135740
Variants:
dbSNP: 6553
ClinVar: 6553
TCGA: ENSG00000135740
COSMIC: SLC9A5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA27745 | ELF2 | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31595389 | 2019 | NHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cells. | 10 |
| 31595389 | 2019 | NHE5 regulates growth factor signaling, integrin trafficking, and degradation in glioma cells. | 10 |
| 24936055 | 2014 | Activation of AMP-activated protein kinase regulates hippocampal neuronal pH by recruiting Na(+)/H(+) exchanger NHE5 to the cell surface. | 9 |
| 24936055 | 2014 | Activation of AMP-activated protein kinase regulates hippocampal neuronal pH by recruiting Na(+)/H(+) exchanger NHE5 to the cell surface. | 9 |
| 21296876 | 2011 | CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. | 7 |
| 21551074 | 2011 | Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5. | 27 |
| 21296876 | 2011 | CK2 phosphorylation of an acidic Ser/Thr di-isoleucine motif in the Na+/H+ exchanger NHE5 isoform promotes association with beta-arrestin2 and endocytosis. | 7 |
| 21551074 | 2011 | Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5. | 27 |
| 19276089 | 2009 | Secretory Carrier Membrane Protein 2 Regulates Cell-surface Targeting of Brain-enriched Na+/H+ Exchanger NHE5. | 16 |
| 19276089 | 2009 | Secretory Carrier Membrane Protein 2 Regulates Cell-surface Targeting of Brain-enriched Na+/H+ Exchanger NHE5. | 16 |
| 16920332 | 2007 | RACK1 associates with NHE5 in focal adhesions and positively regulates the transporter activity. | 15 |
| 16920332 | 2007 | RACK1 associates with NHE5 in focal adhesions and positively regulates the transporter activity. | 15 |
| 15699339 | 2005 | beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform. | 20 |
| 15699339 | 2005 | beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform. | 20 |
| 12205089 | 2002 | Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton. | 19 |
Citation
Dessen P
SLC9A5 (solute carrier family 9 member A5)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73496/slc9a5-(solute-carrier-family-9-member-a5)
