Identity
HGNC
LOCATION
12p12.2
LOCUSID
ALIAS
OATP-F,OATP1,OATP14,OATP1C1,OATPF,OATPRP5,SLC21A14
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 53919
MIM: 613389
HGNC: 13819
Ensembl: ENSG00000139155
Variants:
dbSNP: 53919
ClinVar: 53919
TCGA: ENSG00000139155
COSMIC: SLCO1C1
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 23651021, 25403996, 25493569 | |
| PA443434 | Arthritis, Rheumatoid | Disease | ClinicalAnnotation | associated | PD | 23651021, 25403996, 25493569 | |
| PA446198 | Arthritis, Psoriatic | Disease | ClinicalAnnotation | associated | PD | 23651021, 25403996, 25493569 | |
| PA449515 | etanercept | Chemical | ClinicalAnnotation | associated | PD | 23651021, 25403996, 25493569 | |
| PA452639 | infliximab | Chemical | ClinicalAnnotation | associated | PD | 23651021, 25403996, 25493569 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36621146 | 2023 | Single nucleotide polymorphisms in ADAM17, IL23R and SLCO1C1 genes protect against infliximab failure in adults with Crohn's disease. | 5 |
| 36834621 | 2023 | Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Pyramidal Neurons and Interneurons in the Adult Motor Cortex of Human and Macaque Brain. | 6 |
| 37298594 | 2023 | Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains. | 2 |
| 36621146 | 2023 | Single nucleotide polymorphisms in ADAM17, IL23R and SLCO1C1 genes protect against infliximab failure in adults with Crohn's disease. | 5 |
| 36834621 | 2023 | Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Pyramidal Neurons and Interneurons in the Adult Motor Cortex of Human and Macaque Brain. | 6 |
| 37298594 | 2023 | Thyroid Hormone Transporters MCT8 and OATP1C1 Are Expressed in Projection Neurons and Interneurons of Basal Ganglia and Motor Thalamus in the Adult Human and Macaque Brains. | 2 |
| 32807452 | 2020 | Deiodinases, organic anion transporter polypeptide polymorphisms and symptoms of anxiety and depression after ischemic stroke. | 5 |
| 32807452 | 2020 | Deiodinases, organic anion transporter polypeptide polymorphisms and symptoms of anxiety and depression after ischemic stroke. | 5 |
| 31677555 | 2019 | Deiodinases, organic anion transporter polypeptide polymorphisms and ischemic stroke outcomes. | 4 |
| 31677555 | 2019 | Deiodinases, organic anion transporter polypeptide polymorphisms and ischemic stroke outcomes. | 4 |
| 27180831 | 2016 | Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort. | 7 |
| 27180831 | 2016 | Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in a large UK rheumatoid arthritis cohort. | 7 |
| 25403996 | 2015 | Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis. | 8 |
| 25403996 | 2015 | Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis. | 8 |
| 23651021 | 2013 | GWAS replication study confirms the association of PDE3A-SLCO1C1 with anti-TNF therapy response in rheumatoid arthritis. | 33 |
Citation
Dessen P
SLCO1C1 (solute carrier organic anion transporter family member 1C1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73505/slco1c1-(solute-carrier-organic-anion-transporter-family-member-1c1)
