SLN (sarcolipin)

2014-11-01  

Identity

HGNC
SLN
LOCATION
11q22.3
LOCUSID
6588
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6588
MIM: 602203
HGNC: 11089
Ensembl: ENSG00000170290

Variants:

dbSNP: 6588
ClinVar: 6588
TCGA: ENSG00000170290
COSMIC: SLN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170290ENST00000305991O00631
ENSG00000170290ENST00000305991A0A158RFT9
ENSG00000170290ENST00000525934O00631
ENSG00000170290ENST00000525934A0A158RFT9
ENSG00000170290ENST00000531293O00631
ENSG00000170290ENST00000531293A0A158RFT9

Expression (GTEx)

0
500
1000
1500
2000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Muscle contractionREACTOMER-HSA-397014
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Ion transport by P-type ATPasesREACTOMER-HSA-936837
Cardiac conductionREACTOMER-HSA-5576891
Ion homeostasisREACTOMER-HSA-5578775

References

Pubmed IDYearTitleCitations
332448012021Effects of amino acid modifications on the permeability of the pentameric sarcolipin channel.2
332448012021Effects of amino acid modifications on the permeability of the pentameric sarcolipin channel.2
316746942020Sarcolipin expression in human skeletal muscle: Influence of energy balance and exercise.2
316746942020Sarcolipin expression in human skeletal muscle: Influence of energy balance and exercise.2
282414002017Self-assembling study of sarcolipin and its mutants in multiple molecular dynamic simulations.4
284873732017Interactions between small ankyrin 1 and sarcolipin coordinately regulate activity of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1).13
295948592017Structure-Function Relationship of the SERCA Pump and Its Regulation by Phospholamban and Sarcolipin.13
282414002017Self-assembling study of sarcolipin and its mutants in multiple molecular dynamic simulations.4
284873732017Interactions between small ankyrin 1 and sarcolipin coordinately regulate activity of the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA1).13
295948592017Structure-Function Relationship of the SERCA Pump and Its Regulation by Phospholamban and Sarcolipin.13
265222872016Molecular dynamics of water and monovalent-ions transportation mechanisms of pentameric sarcolipin.1
267437152016Phospholamban and sarcolipin: Are they functionally redundant or distinct regulators of the Sarco(Endo)Plasmic Reticulum Calcium ATPase?42
273780832016Transmembrane dynamics of the Thr-5 phosphorylated sarcolipin pentameric channel.4
265222872016Molecular dynamics of water and monovalent-ions transportation mechanisms of pentameric sarcolipin.1
267437152016Phospholamban and sarcolipin: Are they functionally redundant or distinct regulators of the Sarco(Endo)Plasmic Reticulum Calcium ATPase?42

Citation

Dessen P

SLN (sarcolipin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73529/sln-(sarcolipin)