Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55181
MIM: 613175
HGNC: 25551
Ensembl: ENSG00000167447
Variants:
dbSNP: 55181
ClinVar: 55181
TCGA: ENSG00000167447
COSMIC: SMG8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34761517 | 2022 | Expanding the phenotypic and allelic spectrum of SMG8: Clinical observations reveal overlap with SMG9-associated disease trait. | 2 |
| 34761517 | 2022 | Expanding the phenotypic and allelic spectrum of SMG8: Clinical observations reveal overlap with SMG9-associated disease trait. | 2 |
| 32469312 | 2020 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. | 16 |
| 33242396 | 2020 | Recessive, Deleterious Variants in SMG8 Expand the Role of Nonsense-Mediated Decay in Developmental Disorders in Humans. | 14 |
| 32469312 | 2020 | Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity. | 16 |
| 33242396 | 2020 | Recessive, Deleterious Variants in SMG8 Expand the Role of Nonsense-Mediated Decay in Developmental Disorders in Humans. | 14 |
| 31729466 | 2019 | Cryo-EM structure of SMG1-SMG8-SMG9 complex. | 13 |
| 31792449 | 2019 | InsP(6) binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. | 20 |
| 31729466 | 2019 | Cryo-EM structure of SMG1-SMG8-SMG9 complex. | 13 |
| 31792449 | 2019 | InsP(6) binding to PIKK kinases revealed by the cryo-EM structure of an SMG1-SMG8-SMG9 complex. | 20 |
| 23983263 | 2013 | Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity. | 20 |
| 23983263 | 2013 | Inhibition of SMG-8, a subunit of SMG-1 kinase, ameliorates nonsense-mediated mRNA decay-exacerbated mutant phenotypes without cytotoxicity. | 20 |
| 21245168 | 2011 | The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. | 43 |
| 21245168 | 2011 | The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. | 43 |
Citation
Dessen P
SMG8 (SMG8 nonsense mediated mRNA decay factor)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73558/smg8-(smg8-nonsense-mediated-mrna-decay-factor)
