SNX8 (sorting nexin 8)

2014-11-01  

Identity

HGNC
LOCATION
7p22.3
LOCUSID
ALIAS
Mvp1
FUSION GENES

Other Information

Locus ID:

NCBI: 29886
MIM: 614905
HGNC: 14972
Ensembl: ENSG00000106266

Variants:

dbSNP: 29886
ClinVar: 29886
TCGA: ENSG00000106266
COSMIC: SNX8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106266ENST00000222990Q9Y5X2
ENSG00000106266ENST00000419693C9IYC5
ENSG00000106266ENST00000435060C9J271
ENSG00000106266ENST00000435336C9J8E6
ENSG00000106266ENST00000447136C9JCB9
ENSG00000106266ENST00000457286C9J014

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385194722024SNX8 enables lysosome reformation and reverses lysosomal storage disorder.0
385194722024SNX8 enables lysosome reformation and reverses lysosomal storage disorder.0
342312392021Fatty Acid Synthase-Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD.24
345240842021A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling.14
342312392021Fatty Acid Synthase-Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD.24
345240842021A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling.14
291804172017SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes.17
291804172017SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes.17
243115142014SNX8: A candidate gene for 7p22 cardiac malformations including tetralogy of fallot.3
243115142014SNX8: A candidate gene for 7p22 cardiac malformations including tetralogy of fallot.3
219730562012SNX-BAR-mediated endosome tubulation is co-ordinated with endosome maturation.79
219730562012SNX-BAR-mediated endosome tubulation is co-ordinated with endosome maturation.79

Citation

Dessen P

SNX8 (sorting nexin 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74064/snx8-(sorting-nexin-8)