Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 22986
MIM: 606285
HGNC: 16699
Ensembl: ENSG00000156395
Variants:
dbSNP: 22986
ClinVar: 22986
TCGA: ENSG00000156395
COSMIC: SORCS3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000156395 | ENST00000369699 | Q9UPU3 |
| ENSG00000156395 | ENST00000369701 | Q9UPU3 |
| ENSG00000156395 | ENST00000393176 | Q5CAJ2 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36702997 | 2023 | Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. | 101 |
| 36833409 | 2023 | Independent Associated SNPs at SORCS3 and Its Protein Interactors for Multiple Brain-Related Disorders and Traits. | 2 |
| 36702997 | 2023 | Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains. | 101 |
| 36833409 | 2023 | Independent Associated SNPs at SORCS3 and Its Protein Interactors for Multiple Brain-Related Disorders and Traits. | 2 |
| 35393432 | 2022 | SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression. | 5 |
| 35940132 | 2022 | Cryo-EM structure studies of the human VPS10 domain-containing receptor SorCS3. | 1 |
| 35393432 | 2022 | SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression. | 5 |
| 35940132 | 2022 | Cryo-EM structure studies of the human VPS10 domain-containing receptor SorCS3. | 1 |
| 32966694 | 2021 | Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women. | 15 |
| 32966694 | 2021 | Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women. | 15 |
| 30586538 | 2018 | The SORCS3 gene is mutated in brothers with infantile spasms and intellectual disability. | 5 |
| 30586538 | 2018 | The SORCS3 gene is mutated in brothers with infantile spasms and intellectual disability. | 5 |
| 28827148 | 2017 | Hidden Twins: SorCS Neuroreceptors Form Stable Dimers. | 10 |
| 28827148 | 2017 | Hidden Twins: SorCS Neuroreceptors Form Stable Dimers. | 10 |
| 26362888 | 2016 | Genetic analysis of the isolated Faroe Islands reveals SORCS3 as a potential multiple sclerosis risk gene. | 3 |
Citation
Dessen P
SORCS3 (sortilin related VPS10 domain containing receptor 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74073/sorcs3-(sortilin-related-vps10-domain-containing-receptor-3)
