SPATC1L (spermatogenesis and centriole associated 1 like)

2014-11-01  

Identity

HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
C21orf56
FUSION GENES

Other Information

Locus ID:

NCBI: 84221
MIM: 612412
HGNC: 1298
Ensembl: ENSG00000160284

Variants:

dbSNP: 84221
ClinVar: 84221
TCGA: ENSG00000160284
COSMIC: SPATC1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160284ENST00000291672Q9H0A9
ENSG00000160284ENST00000330205Q9H0A9

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
376255672023Balanced chromosomal rearrangements implicate YIPF5 and SPATC1L in non-obstructive oligoasthenozoospermia and oligozoospermia and of a derivative chromosome 22 in recurrent miscarriage.0
376255672023Balanced chromosomal rearrangements implicate YIPF5 and SPATC1L in non-obstructive oligoasthenozoospermia and oligozoospermia and of a derivative chromosome 22 in recurrent miscarriage.0
342134892022Biallelic mutations in spermatogenesis and centriole-associated 1 like (SPATC1L) cause acephalic spermatozoa syndrome and male infertility.5
342134892022Biallelic mutations in spermatogenesis and centriole-associated 1 like (SPATC1L) cause acephalic spermatozoa syndrome and male infertility.5
331524452021PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L.10
331524452021PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L.10
301777752019Next-generation sequencing identified SPATC1L as a possible candidate gene for both early-onset and age-related hearing loss.9
301777752019Next-generation sequencing identified SPATC1L as a possible candidate gene for both early-onset and age-related hearing loss.9
300263082018SPATC1L maintains the integrity of the sperm head-tail junction.20
300263082018SPATC1L maintains the integrity of the sperm head-tail junction.20
283390092017Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.7
288492232017Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome‑wide association study.5
283390092017Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.7
288492232017Identification of TNFSF13, SPATC1L, SLC22A25 and SALL4 as novel susceptibility loci for atrial fibrillation by an exome‑wide association study.5

Citation

Dessen P

SPATC1L (spermatogenesis and centriole associated 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74149/spatc1l-(spermatogenesis-and-centriole-associated-1-like)