Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54908
MIM: 616401
HGNC: 26010
Ensembl: ENSG00000040275
Variants:
dbSNP: 54908
ClinVar: 54908
TCGA: ENSG00000040275
COSMIC: SPDL1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33758299 | 2021 | Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis. | 26 |
| 33758299 | 2021 | Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis. | 26 |
| 33543222 | 2020 | [Expression and clinical significance of Spindly and Bub3 in oral squamous cell carcinoma]. | 3 |
| 33543222 | 2020 | [Expression and clinical significance of Spindly and Bub3 in oral squamous cell carcinoma]. | 3 |
| 31690663 | 2019 | MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM. | 16 |
| 31690663 | 2019 | MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM. | 16 |
| 30258100 | 2018 | USP45 and Spindly are part of the same complex implicated in cell migration. | 7 |
| 30258100 | 2018 | USP45 and Spindly are part of the same complex implicated in cell migration. | 7 |
| 25808490 | 2015 | Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. | 25 |
| 25825516 | 2015 | A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores. | 35 |
| 25808490 | 2015 | Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. | 25 |
| 25825516 | 2015 | A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores. | 35 |
| 20427577 | 2010 | Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation. | 77 |
| 20439434 | 2010 | Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. | 108 |
| 20427577 | 2010 | Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation. | 77 |
Citation
Dessen P
SPDL1 (spindle apparatus coiled-coil protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74156/spdl1-(spindle-apparatus-coiled-coil-protein-1)
