SPINK4 (serine peptidase inhibitor Kazal type 4)

2014-11-01  

Identity

HGNC
SPINK4
LOCATION
9p13.3
LOCUSID
27290
ALIAS
HEL136,PEC-60,PEC60
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27290
MIM: 613929
HGNC: 16646
Ensembl: ENSG00000122711

Variants:

dbSNP: 27290
ClinVar: 27290
TCGA: ENSG00000122711
COSMIC: SPINK4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000122711ENST00000379721O60575
ENSG00000122711ENST00000379721V9HWG8
ENSG00000122711ENST00000379725Q5VZE7

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
318885702019Downregulated SPINK4 is associated with poor survival in colorectal cancer.13
318885702019Downregulated SPINK4 is associated with poor survival in colorectal cancer.13
173331662007The SPINK gene family and celiac disease susceptibility.23
173331662007The SPINK gene family and celiac disease susceptibility.23

Citation

Dessen P

SPINK4 (serine peptidase inhibitor Kazal type 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74183/spink4-(serine-peptidase-inhibitor-kazal-type-4)