Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 339745
HGNC: 27934
Ensembl: ENSG00000144228
Variants:
dbSNP: 339745
ClinVar: 339745
TCGA: ENSG00000144228
COSMIC: SPOPL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000144228 | ENST00000280098 | Q6IQ16 |
| ENSG00000144228 | ENST00000420679 | F8WD02 |
| ENSG00000144228 | ENST00000430968 | F8WBB7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | ||
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37523046 | 2023 | SPOPL induces tumorigenicity and stemness in glioma stem cells by activating Notch signaling. | 1 |
| 37523046 | 2023 | SPOPL induces tumorigenicity and stemness in glioma stem cells by activating Notch signaling. | 1 |
| 27008177 | 2016 | A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. | 32 |
| 27008177 | 2016 | A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. | 32 |
Citation
Dessen P
SPOPL (speckle type BTB/POZ protein like)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74196/spopl-(speckle-type-btb-poz-protein-like)
