Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 162540
MIM: 608284
HGNC: 28902
Ensembl: ENSG00000185294
Variants:
dbSNP: 162540
ClinVar: 162540
TCGA: ENSG00000185294
COSMIC: SPPL2C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000185294 | ENST00000329196 | Q8IUH8 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33637690 | 2021 | Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. | 8 |
| 33637690 | 2021 | Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease. | 8 |
| 30733280 | 2019 | The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban. | 16 |
| 30733281 | 2019 | Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins. | 4 |
| 30733280 | 2019 | The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban. | 16 |
| 30733281 | 2019 | Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins. | 4 |
| 16415175 | 2006 | High throughput SNP and expression analyses of candidate genes for non-syndromic oral clefts. | 25 |
| 16415175 | 2006 | High throughput SNP and expression analyses of candidate genes for non-syndromic oral clefts. | 25 |
| 15293277 | 2004 | Novel haplotypes in 17q21 are associated with progressive supranuclear palsy. | 21 |
| 15385547 | 2004 | Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. | 44 |
| 15293277 | 2004 | Novel haplotypes in 17q21 are associated with progressive supranuclear palsy. | 21 |
| 15385547 | 2004 | Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. | 44 |
Citation
Dessen P
SPPL2C (signal peptide peptidase like 2C)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74198/meetings/submit-meetings/
