SPRY3 (sprouty RTK signaling antagonist 3)

2014-11-01  

Identity

HGNC
SPRY3
LOCATION
Xq28
LOCUSID
10251
ALIAS
spry-3

Other Information

Locus ID:

NCBI: 10251
MIM: 300531
HGNC: 11271
Ensembl: ENSG00000168939

Variants:

dbSNP: 10251
ClinVar: 10251
TCGA: ENSG00000168939
COSMIC: SPRY3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168939ENST00000302805O43610

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
347693782021Sprouty3, but Not Sprouty1, Expression Is Beneficial for the Malignant Potential of Osteosarcoma Cells.1
347693782021Sprouty3, but Not Sprouty1, Expression Is Beneficial for the Malignant Potential of Osteosarcoma Cells.1
313748602019Sprouty3 and Sprouty4, Two Members of a Family Known to Inhibit FGF-Mediated Signaling, Exert Opposing Roles on Proliferation and Migration of Glioblastoma-Derived Cells.14
313748602019Sprouty3 and Sprouty4, Two Members of a Family Known to Inhibit FGF-Mediated Signaling, Exert Opposing Roles on Proliferation and Migration of Glioblastoma-Derived Cells.14
260892022015Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region.9
260892022015Regulation of SPRY3 by X chromosome and PAR2-linked promoters in an autism susceptibility region.9
168773792006A functional interaction between sprouty proteins and caveolin-1.14
168773792006A functional interaction between sprouty proteins and caveolin-1.14
159500612005Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching.29
159500612005Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching.29

Citation

Dessen P

SPRY3 (sprouty RTK signaling antagonist 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74210/spry3-(sprouty-rtk-signaling-antagonist-3)