Identity
HGNC
LOCATION
5q12.3
LOCUSID
ALIAS
SFRS12,SRrp508,SRrp86
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 140890
MIM: 609268
HGNC: 17882
Ensembl: ENSG00000153914
Variants:
dbSNP: 140890
ClinVar: 140890
TCGA: ENSG00000153914
COSMIC: SREK1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35296659 | 2022 | The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma. | 16 |
| 35296659 | 2022 | The aberrant upregulation of exon 10-inclusive SREK1 through SRSF10 acts as an oncogenic driver in human hepatocellular carcinoma. | 16 |
| 34556983 | 2021 | The rs74794265 SNP of the SREK1 Gene is Associated with COPD in Kashi, China. | 3 |
| 34556983 | 2021 | The rs74794265 SNP of the SREK1 Gene is Associated with COPD in Kashi, China. | 3 |
| 32533168 | 2020 | Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism. | 12 |
| 32533168 | 2020 | Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism. | 12 |
| 20400856 | 2010 | Analysis of SRrp86-regulated alternative splicing: control of c-Jun and IκBβ activity. | 2 |
| 20400856 | 2010 | Analysis of SRrp86-regulated alternative splicing: control of c-Jun and IκBβ activity. | 2 |
| 15456940 | 2004 | The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain. | 3 |
| 15456940 | 2004 | The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain. | 3 |
| 11991645 | 2002 | Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. | 8 |
| 12183448 | 2002 | A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor. | 9 |
| 11991645 | 2002 | Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. | 8 |
| 12183448 | 2002 | A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor. | 9 |
Citation
Dessen P
SREK1 (splicing regulatory glutamic acid and lysine rich protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74227/srek1-(splicing-regulatory-glutamic-acid-and-lysine-rich-protein-1)
