STARD8 (StAR related lipid transfer domain containing 8)

2014-11-01  

Identity

HGNC
LOCATION
Xq13.1
LOCUSID
ALIAS
ARHGAP38,DLC3,STARTGAP3

Other Information

Locus ID:

NCBI: 9754
MIM: 300689
HGNC: 19161
Ensembl: ENSG00000130052

Variants:

dbSNP: 9754
ClinVar: 9754
TCGA: ENSG00000130052
COSMIC: STARD8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130052ENST00000252336Q92502
ENSG00000130052ENST00000374597Q92502
ENSG00000130052ENST00000374599Q92502
ENSG00000130052ENST00000523864E5RFN7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379825682024PYCR1, BANF1, and STARD8 Expression in Gastric Carcinoma: A Clinicopathologic, Prognostic, and Immunohistochemical Study.0
380918852024Regional bias of tumor suppressor gene mutations of STARD8 and WNK2 in colon cancers.0
379825682024PYCR1, BANF1, and STARD8 Expression in Gastric Carcinoma: A Clinicopathologic, Prognostic, and Immunohistochemical Study.0
380918852024Regional bias of tumor suppressor gene mutations of STARD8 and WNK2 in colon cancers.0
363260912022A conserved function of Human DLC3 and Drosophila Cv-c in testis development.2
363260912022A conserved function of Human DLC3 and Drosophila Cv-c in testis development.2
310765132019DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes.6
310765132019DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes.6
275058942016The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling.18
275058942016The polarity protein Scribble positions DLC3 at adherens junctions to regulate Rho signaling.18
256738742015The Rho-specific GAP protein DLC3 coordinates endocytic membrane trafficking.0
256738742015The Rho-specific GAP protein DLC3 coordinates endocytic membrane trafficking.0
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

STARD8 (StAR related lipid transfer domain containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74299/stard8-(star-related-lipid-transfer-domain-containing-8)