Identity
HGNC
LOCATION
7q11.23
LOCUSID
ALIAS
DUSP24,MK-STYX,MKSTYX
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51657
MIM: 616695
HGNC: 18165
Ensembl: ENSG00000127952
Variants:
dbSNP: 51657
ClinVar: 51657
TCGA: ENSG00000127952
COSMIC: STYXL1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37198709 | 2023 | Pseudophosphatase STYXL1 depletion enhances glucocerebrosidase trafficking to lysosomes via ER stress. | 0 |
| 37516290 | 2023 | The DUSP domain of pseudophosphatase MK-STYX interacts with G3BP1 to decrease stress granules. | 1 |
| 37198709 | 2023 | Pseudophosphatase STYXL1 depletion enhances glucocerebrosidase trafficking to lysosomes via ER stress. | 0 |
| 37516290 | 2023 | The DUSP domain of pseudophosphatase MK-STYX interacts with G3BP1 to decrease stress granules. | 1 |
| 32271415 | 2020 | STYXL1 promotes malignant progression of hepatocellular carcinoma via downregulating CELF2 through the PI3K/Akt pathway. | 10 |
| 32271415 | 2020 | STYXL1 promotes malignant progression of hepatocellular carcinoma via downregulating CELF2 through the PI3K/Akt pathway. | 10 |
| 30472486 | 2019 | A previously identified missense mutation in STYXL1 is likely benign. | 1 |
| 31146910 | 2019 | Serine/threonine/tyrosine-interacting-like protein 1 (STYXL1), a pseudo phosphatase, promotes oncogenesis in glioma. | 8 |
| 30472486 | 2019 | A previously identified missense mutation in STYXL1 is likely benign. | 1 |
| 31146910 | 2019 | Serine/threonine/tyrosine-interacting-like protein 1 (STYXL1), a pseudo phosphatase, promotes oncogenesis in glioma. | 8 |
| 25724587 | 2015 | Homozygous missense mutation in STYXL1 associated with moderate intellectual disability, epilepsy and behavioural complexities. | 5 |
| 25724587 | 2015 | Homozygous missense mutation in STYXL1 associated with moderate intellectual disability, epilepsy and behavioural complexities. | 5 |
| 24709986 | 2014 | The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1. | 12 |
| 24709986 | 2014 | The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1. | 12 |
| 23163895 | 2013 | The pseudophosphatase MK-STYX inhibits stress granule assembly independently of Ser149 phosphorylation of G3BP-1. | 15 |
Citation
Dessen P
STYXL1 (serine/threonine/tyrosine interacting like 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74350/styxl1-(serine-threonine-tyrosine-interacting-like-1)
