Identity
HGNC
LOCATION
13q14.2
LOCUSID
ALIAS
A-BETA,A-SCS,LINC00444,MTDPS5,SCS-betaA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8803
MIM: 603921
HGNC: 11448
Ensembl: ENSG00000136143
Variants:
dbSNP: 8803
ClinVar: 8803
TCGA: ENSG00000136143
COSMIC: SUCLA2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33231368 | 2021 | SUCLA2 Arg407Trp mutation can cause a nonprogressive movement disorder - deafness syndrome. | 4 |
| 33991485 | 2021 | SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells. | 60 |
| 33231368 | 2021 | SUCLA2 Arg407Trp mutation can cause a nonprogressive movement disorder - deafness syndrome. | 4 |
| 33991485 | 2021 | SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells. | 60 |
| 32694611 | 2020 | Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion. | 7 |
| 33230181 | 2020 | SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. | 27 |
| 32694611 | 2020 | Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion. | 7 |
| 33230181 | 2020 | SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. | 27 |
| 28749033 | 2017 | Co-occurring Down syndrome and SUCLA2-related mitochondrial depletion syndrome. | 0 |
| 28749033 | 2017 | Co-occurring Down syndrome and SUCLA2-related mitochondrial depletion syndrome. | 0 |
| 26475597 | 2016 | Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1: phenotype and genotype correlations in 71 patients. | 35 |
| 26863601 | 2016 | Influences of XDH genotype by gene-gene interactions with SUCLA2 for thiopurine-induced leukopenia in Korean patients with Crohn's disease. | 5 |
| 27484306 | 2016 | Expanding the phenotypic spectrum of Succinyl-CoA ligase deficiency through functional validation of a new SUCLG1 variant. | 8 |
| 27766610 | 2016 | Knockdown of Sucla2 decreases the viability of mouse spermatocytes by inducing apoptosis through injury of the mitochondrial function of cells. | 1 |
| 26475597 | 2016 | Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1: phenotype and genotype correlations in 71 patients. | 35 |
Citation
Dessen P
SUCLA2 (succinate-CoA ligase ADP-forming subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74351/sucla2-(succinate-coa-ligase-adp-forming-subunit-beta)
