SUGCT (succinyl-CoA:glutarate-CoA transferase)

2014-11-01  

Identity

HGNC
SUGCT
LOCATION
7p14.1
LOCUSID
79783
ALIAS
C7orf10,DERP13,GA3,ORF19
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79783
MIM: 609187
HGNC: 16001
Ensembl: ENSG00000175600

Variants:

dbSNP: 79783
ClinVar: 79783
TCGA: ENSG00000175600
COSMIC: SUGCT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175600ENST00000335693Q9HAC7
ENSG00000175600ENST00000401647Q9HAC7
ENSG00000175600ENST00000413931H7C0H3
ENSG00000175600ENST00000416370H0Y4N1
ENSG00000175600ENST00000444074H7C1N0
ENSG00000175600ENST00000628514Q9HAC7

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA452637hormonal contraceptives for systemic useChemicalClinicalAnnotationassociatedPD28750087

References

Pubmed IDYearTitleCitations
334832542021Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains.2
334832542021Glutaric aciduria type 3 is a naturally occurring biochemical trait in inbred mice of 129 substrains.2
294216012018Novel contiguous gene deletion in peruvian girl with Trichothiodystrophy type 4 and glutaric aciduria type 3.8
294216012018Novel contiguous gene deletion in peruvian girl with Trichothiodystrophy type 4 and glutaric aciduria type 3.8
238930492014C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, the enzyme that converts glutarate to glutaryl-CoA.26
238930492014C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, the enzyme that converts glutarate to glutaryl-CoA.26
222779672012Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.201
222779672012Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.201
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

SUGCT (succinyl-CoA:glutarate-CoA transferase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74358/sugct-(succinyl-coa-glutarate-coa-transferase)