SULT1C4 (sulfotransferase family 1C member 4)

2014-11-01  

Identity

HGNC
LOCATION
2q12.3
LOCUSID
ALIAS
SULT1C,SULT1C2

Other Information

Locus ID:

NCBI: 27233
MIM: 608357
HGNC: 11457
Ensembl: ENSG00000198075

Variants:

dbSNP: 27233
ClinVar: 27233
TCGA: ENSG00000198075
COSMIC: SULT1C4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198075ENST00000272452O75897
ENSG00000198075ENST00000409309O75897

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA445425Prostatic NeoplasmsDiseaseClinicalAnnotationassociatedPD20038957
PA449383docetaxelChemicalClinicalAnnotationassociatedPD20038957
PA451644thalidomideChemicalClinicalAnnotationassociatedPD20038957

References

Pubmed IDYearTitleCitations
352494342023Sulfation of hyperoside by the human cytosolic sulfotransferases (SULTs): impact of genetic polymorphisms on hyperoside-sulfating activity of SULT1C4 allozymes.0
368803642023Sulfotransferase 1C2 promotes hepatocellular carcinoma progression by enhancing glycolysis and fatty acid metabolism.2
352494342023Sulfation of hyperoside by the human cytosolic sulfotransferases (SULTs): impact of genetic polymorphisms on hyperoside-sulfating activity of SULT1C4 allozymes.0
368803642023Sulfotransferase 1C2 promotes hepatocellular carcinoma progression by enhancing glycolysis and fatty acid metabolism.2
323035762020Developmental Expression of SULT1C4 Transcript Variants in Human Liver: Implications for Discordance Between SULT1C4 mRNA and Protein Levels.4
323035762020Developmental Expression of SULT1C4 Transcript Variants in Human Liver: Implications for Discordance Between SULT1C4 mRNA and Protein Levels.4
269489522016Human cytosolic sulfotransferase SULT1C4 mediates the sulfation of doxorubicin and epirubicin.4
269489522016Human cytosolic sulfotransferase SULT1C4 mediates the sulfation of doxorubicin and epirubicin.4
260674752015Sulphation of acetaminophen by the human cytosolic sulfotransferases: a systematic analysis.18
260674752015Sulphation of acetaminophen by the human cytosolic sulfotransferases: a systematic analysis.18

Citation

Dessen P

SULT1C4 (sulfotransferase family 1C member 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74368/sult1c4-(sulfotransferase-family-1c-member-4)