SUMF2 (sulfatase modifying factor 2)

2014-11-01  

Identity

HGNC
LOCATION
7p11.2
LOCUSID
ALIAS
pFGE
FUSION GENES

Other Information

Locus ID:

NCBI: 25870
MIM: 607940
HGNC: 20415
Ensembl: ENSG00000129103

Variants:

dbSNP: 25870
ClinVar: 25870
TCGA: ENSG00000129103
COSMIC: SUMF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129103ENST00000275607Q8NBJ7
ENSG00000129103ENST00000275607A0A024RDK8
ENSG00000129103ENST00000342190Q8NBJ7
ENSG00000129103ENST00000395435Q8NBJ7
ENSG00000129103ENST00000395436A8MXB9
ENSG00000129103ENST00000413756C9J660
ENSG00000129103ENST00000413952C9JL30
ENSG00000129103ENST00000423763F8WEX5
ENSG00000129103ENST00000434526Q8NBJ7
ENSG00000129103ENST00000436782F8WEV7
ENSG00000129103ENST00000437307E9PBT8
ENSG00000129103ENST00000438133F8WES7
ENSG00000129103ENST00000447501E9PG02
ENSG00000129103ENST00000451338H7C3B2
ENSG00000129103ENST00000452216F8WCW9
ENSG00000129103ENST00000650735J3QT17
ENSG00000129103ENST00000651354J3KQJ1
ENSG00000129103ENST00000651586A0A494C1B1
ENSG00000129103ENST00000652303F8WA42

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Gamma carboxylation, hypusine formation and arylsulfatase activationREACTOMER-HSA-163841
The activation of arylsulfatasesREACTOMER-HSA-1663150
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Sphingolipid metabolismREACTOMER-HSA-428157
Glycosphingolipid metabolismREACTOMER-HSA-1660662

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
353170992022Differential DNA methylation analysis of SUMF2, ADAMTS5, and PXDN provides novel insights into colorectal cancer prognosis prediction in Taiwan.3
353170992022Differential DNA methylation analysis of SUMF2, ADAMTS5, and PXDN provides novel insights into colorectal cancer prognosis prediction in Taiwan.3
197390972009SUMF2 interacts with interleukin-13 and inhibits interleukin-13 secretion in bronchial smooth muscle cells.5
197390972009SUMF2 interacts with interleukin-13 and inhibits interleukin-13 secretion in bronchial smooth muscle cells.5
182667662008Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals.7
182667662008Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals.7
156874892005Crystal structure of human pFGE, the paralog of the Calpha-formylglycine-generating enzyme.11
157088612005Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.6
159620102005Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2.19
156874892005Crystal structure of human pFGE, the paralog of the Calpha-formylglycine-generating enzyme.11
157088612005Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.6
159620102005Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2.19

Citation

Dessen P

SUMF2 (sulfatase modifying factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74372/sumf2-(sulfatase-modifying-factor-2)