SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1)

2014-11-01  

Identity

HGNC
LOCATION
9q31.3
LOCUSID
ALIAS
C9orf13,CCP22,POLYDOM,SEL-OB,SELOB
FUSION GENES

Other Information

Locus ID:

NCBI: 79987
MIM: 611691
HGNC: 15985
Ensembl: ENSG00000165124

Variants:

dbSNP: 79987
ClinVar: 79987
TCGA: ENSG00000165124
COSMIC: SVEP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165124ENST00000374461Q4LDE5
ENSG00000165124ENST00000374469Q4LDE5
ENSG00000165124ENST00000401783A0A0A0MSD0

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384096112024EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.0
384096112024EGR1 transcriptionally regulates SVEP1 to promote proliferation and migration in human coronary artery smooth muscle cells.0
353069832023Effects of SVEP1 on Lung Squamous Cell Carcinoma and its Association with Tumor Mutation Burden, Prognosis, and Immune Regulation.1
371003522023SVEP1 influences monocyte to macrophage differentiation via integrin α4β1/α9β1 and Rho/Rac signalling.2
353069832023Effects of SVEP1 on Lung Squamous Cell Carcinoma and its Association with Tumor Mutation Burden, Prognosis, and Immune Regulation.1
371003522023SVEP1 influences monocyte to macrophage differentiation via integrin α4β1/α9β1 and Rho/Rac signalling.2
358020722022The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.4
359003192022Decreased expression of SVEP1 is closely related to a cancer stem cell-like phenotype and poor prognosis in hepatocellular carcinoma.1
358020722022The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.4
359003192022Decreased expression of SVEP1 is closely related to a cancer stem cell-like phenotype and poor prognosis in hepatocellular carcinoma.1
337624332021SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.24
343091842021A genome-wide association study identifying SVEP1 variant as a predictor of response to tolvaptan for cirrhotic ascites.1
345060842021SVEP1 is important for morphogenesis of lymphatic system: Possible implications in lymphedema.6
337624332021SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.24
343091842021A genome-wide association study identifying SVEP1 variant as a predictor of response to tolvaptan for cirrhotic ascites.1

Citation

Dessen P

SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74389/svep1-(sushi-von-willebrand-factor-type-a-egf-and-pentraxin-domain-containing-1)