Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 93426
MIM: 611486
HGNC: 28852
Ensembl: ENSG00000171772
Variants:
dbSNP: 93426
ClinVar: 93426
TCGA: ENSG00000171772
COSMIC: SYCE1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171772 | ENST00000303903 | A0A0B4J1R9 |
| ENSG00000171772 | ENST00000343131 | Q8N0S2 |
| ENSG00000171772 | ENST00000368517 | Q8N0S2 |
| ENSG00000171772 | ENST00000432597 | A0A0A0MT28 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell Cycle | REACTOME | R-HSA-1640170 |
| Meiosis | REACTOME | R-HSA-1500620 |
| Meiotic synapsis | REACTOME | R-HSA-1221632 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37957469 | 2024 | Novel Mutations Reduce Expression of Meiotic Regulators SYCE1 and BOLL in Testis of Azoospermic Men from West Bengal, India. | 0 |
| 37957469 | 2024 | Novel Mutations Reduce Expression of Meiotic Regulators SYCE1 and BOLL in Testis of Azoospermic Men from West Bengal, India. | 0 |
| 35718780 | 2022 | Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia. | 3 |
| 35718780 | 2022 | Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia. | 3 |
| 33728612 | 2021 | Targeted next-generation sequencing panel screening of 668 Chinese patients with non-obstructive azoospermia. | 7 |
| 33728612 | 2021 | Targeted next-generation sequencing panel screening of 668 Chinese patients with non-obstructive azoospermia. | 7 |
| 31916078 | 2020 | The second mutation of SYCE1 gene associated with autosomal recessive nonobstructive azoospermia. | 17 |
| 31925770 | 2020 | Consanguineous Chinese Familial Study Reveals that a Gross Deletion that Includes the SYCE1 Gene Region Is Associated with Premature Ovarian Insufficiency. | 10 |
| 31916078 | 2020 | The second mutation of SYCE1 gene associated with autosomal recessive nonobstructive azoospermia. | 17 |
| 31925770 | 2020 | Consanguineous Chinese Familial Study Reveals that a Gross Deletion that Includes the SYCE1 Gene Region Is Associated with Premature Ovarian Insufficiency. | 10 |
| 30607510 | 2019 | Molecular structure of human synaptonemal complex protein SYCE1. | 25 |
| 30607510 | 2019 | Molecular structure of human synaptonemal complex protein SYCE1. | 25 |
| 25899990 | 2015 | Deleterious mutation in SYCE1 is associated with non-obstructive azoospermia. | 49 |
| 25899990 | 2015 | Deleterious mutation in SYCE1 is associated with non-obstructive azoospermia. | 49 |
| 25062452 | 2014 | Exome sequencing reveals SYCE1 mutation associated with autosomal recessive primary ovarian insufficiency. | 71 |
Citation
Dessen P
SYCE1 (synaptonemal complex central element protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74397/syce1-(synaptonemal-complex-central-element-protein-1)
