TAGAP (T cell activation RhoGTPase activating protein)

2014-11-01  

Identity

HGNC
LOCATION
6q25.3
LOCUSID
ALIAS
ARHGAP47,FKSG15,IDDM21,TAGAP1

Other Information

Locus ID:

NCBI: 117289
MIM: 609667
HGNC: 15669
Ensembl: ENSG00000164691

Variants:

dbSNP: 117289
ClinVar: 117289
TCGA: ENSG00000164691
COSMIC: TAGAP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164691ENST00000326965Q8N103
ENSG00000164691ENST00000338313Q8N103
ENSG00000164691ENST00000367066Q8N103
ENSG00000164691ENST00000642909A0A2R8YEB9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377443502023TAGAP expression influences CD4+ T cell differentiation, immune infiltration, and cytotoxicity in LUAD through the STAT pathway: implications for immunotherapy.0
377443502023TAGAP expression influences CD4+ T cell differentiation, immune infiltration, and cytotoxicity in LUAD through the STAT pathway: implications for immunotherapy.0
355975272022An attempt to unravel the association of TAGAP gene SNPs with rheumatoid arthritis in the Indian population using high-resolution melting analysis.0
355975272022An attempt to unravel the association of TAGAP gene SNPs with rheumatoid arthritis in the Indian population using high-resolution melting analysis.0
290177722018T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis.6
293292962018Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study.28
290177722018T cell activation Rho GTPase activating protein (TAGAP) is upregulated in clinical and experimental arthritis.6
293292962018Identification and in silico analysis of functional SNPs of human TAGAP protein: A comprehensive study.28
282085892017Association of LPP and TAGAP Polymorphisms with Celiac Disease Risk: A Meta-Analysis.4
283562292017Association of rs1738074 polymorphism of TAGAP gene with susceptibility to multiple sclerosis in the Iranian population.1
282085892017Association of LPP and TAGAP Polymorphisms with Celiac Disease Risk: A Meta-Analysis.4
283562292017Association of rs1738074 polymorphism of TAGAP gene with susceptibility to multiple sclerosis in the Iranian population.1
267652642016The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.20
267652642016The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.20
245820672014T-cell activation Rho GTPase-activating protein expression varies with inflammation location and severity in Crohn's disease.12

Citation

Dessen P

TAGAP (T cell activation RhoGTPase activating protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74474/tagap-(t-cell-activation-rhogtpase-activating-protein)