Identity
HGNC
LOCATION
22q11.21
LOCUSID
ALIAS
C22orf25,MECRCN
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 128989
MIM: 616830
HGNC: 25439
Ensembl: ENSG00000183597
Variants:
dbSNP: 128989
ClinVar: 128989
TCGA: ENSG00000183597
COSMIC: TANGO2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37721116 | 2024 | Molecular insight into CREBBP and TANGO2 variants causing intellectual disability. | 1 |
| 38718569 | 2024 | Lipidomic analysis of human TANGO2-deficient cells suggests a lipid imbalance as a cause of TANGO2 deficiency disease. | 1 |
| 37721116 | 2024 | Molecular insight into CREBBP and TANGO2 variants causing intellectual disability. | 1 |
| 38718569 | 2024 | Lipidomic analysis of human TANGO2-deficient cells suggests a lipid imbalance as a cause of TANGO2 deficiency disease. | 1 |
| 34668327 | 2022 | Variable clinical severity in TANGO2 deficiency: Case series and literature review. | 13 |
| 35197517 | 2022 | Mitochondrial dysfunction associated with TANGO2 deficiency. | 13 |
| 34668327 | 2022 | Variable clinical severity in TANGO2 deficiency: Case series and literature review. | 13 |
| 35197517 | 2022 | Mitochondrial dysfunction associated with TANGO2 deficiency. | 13 |
| 32909282 | 2021 | The phenotype associated with variants in TANGO2 may be explained by a dual role of the protein in ER-to-Golgi transport and at the mitochondria. | 15 |
| 32929747 | 2021 | Clinical and biological characterization of 20 patients with TANGO2 deficiency indicates novel triggers of metabolic crises and no primary energetic defect. | 17 |
| 33342685 | 2021 | Clinical phenotype associated with TANGO2 gene mutation. | 8 |
| 32909282 | 2021 | The phenotype associated with variants in TANGO2 may be explained by a dual role of the protein in ER-to-Golgi transport and at the mitochondria. | 15 |
| 32929747 | 2021 | Clinical and biological characterization of 20 patients with TANGO2 deficiency indicates novel triggers of metabolic crises and no primary energetic defect. | 17 |
| 33342685 | 2021 | Clinical phenotype associated with TANGO2 gene mutation. | 8 |
| 31339582 | 2020 | Clinical presentation and proteomic signature of patients with TANGO2 mutations. | 28 |
Citation
Dessen P
TANGO2 (transport and golgi organization 2 homolog)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74477/tango2-(transport-and-golgi-organization-2-homolog)
