TAS2R43 (taste 2 receptor member 43)

2014-11-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
T2R43,T2R52

Other Information

Locus ID:

NCBI: 259289
MIM: 612668
HGNC: 18875
Ensembl: ENSG00000255374

Variants:

dbSNP: 259289
ClinVar: 259289
TCGA: ENSG00000255374
COSMIC: TAS2R43

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000255374ENST00000531678P59537

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
347842952022Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity.15
347842952022Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity.15
334612972021Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.12
334612972021Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.12
260374852015A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs.16
263913542015Children's perceptions about medicines: individual differences and taste.16
260374852015A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs.16
263913542015Children's perceptions about medicines: individual differences and taste.16
246473402014Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking.11
246473402014Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking.11
223972212012Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.4
229643022012Extraoral bitter taste receptors as mediators of off-target drug effects.59
230507642012Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN).10
223972212012Patients with phantogeusia show increased expression of T2R taste receptor genes in their tongues.4
229643022012Extraoral bitter taste receptors as mediators of off-target drug effects.59

Citation

Dessen P

TAS2R43 (taste 2 receptor member 43)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74500/tas2r43-(taste-2-receptor-member-43)