TAS2R50 (taste 2 receptor member 50)

2014-11-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
T2R50,T2R51,TAS2R51

Other Information

Locus ID:

NCBI: 259296
MIM: 609627
HGNC: 18882
Ensembl: ENSG00000212126

Variants:

dbSNP: 259296
ClinVar: 259296
TCGA: ENSG00000212126
COSMIC: TAS2R50

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000212126ENST00000506868P59544

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Taste transductionKEGGko04742
Taste transductionKEGGhsa04742
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class C/3 (Metabotropic glutamate/pheromone receptors)REACTOMER-HSA-420499
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594

References

Pubmed IDYearTitleCitations
334332472021Bitter Taste Receptors and Chronic Otitis Media.1
334612972021Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.12
334332472021Bitter Taste Receptors and Chronic Otitis Media.1
334612972021Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture.12
322277022020Polymorphism of TAS2R3, TAS2R5, TAS2R19, and TAS2R50 genes and bitter food intake frequency inelderly woman.1
322277022020Polymorphism of TAS2R3, TAS2R5, TAS2R19, and TAS2R50 genes and bitter food intake frequency inelderly woman.1
283667702017A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture.16
283667702017A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture.16
221925112012KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.15
221925112012KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.15
197097662011Variations of specific non-candidate genes and risk of myocardial infarction: a replication study.7
197097662011Variations of specific non-candidate genes and risk of myocardial infarction: a replication study.7
190230992009Gene variants associated with ischemic stroke: the cardiovascular health study.20
198174112009The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin.29
190230992009Gene variants associated with ischemic stroke: the cardiovascular health study.20

Citation

Dessen P

TAS2R50 (taste 2 receptor member 50)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74503/tas2r50-(taste-2-receptor-member-50)