Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79736
MIM: 616422
HGNC: 26223
Ensembl: ENSG00000172171
Variants:
dbSNP: 79736
ClinVar: 79736
TCGA: ENSG00000172171
COSMIC: TEFM
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172171 | ENST00000306049 | Q96QE5 |
| ENSG00000172171 | ENST00000580840 | J3KTG7 |
| ENSG00000172171 | ENST00000581216 | Q96QE5 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36823193 | 2023 | TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. | 5 |
| 36823193 | 2023 | TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. | 5 |
| 33771980 | 2021 | Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma. | 5 |
| 33771980 | 2021 | Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma. | 5 |
| 29033127 | 2017 | Mechanism of Transcription Anti-termination in Human Mitochondria. | 38 |
| 29033127 | 2017 | Mechanism of Transcription Anti-termination in Human Mitochondria. | 38 |
| 25635099 | 2015 | Mitochondrial biology. Replication-transcription switch in human mitochondria. | 87 |
| 25690892 | 2015 | TEFM is a potent stimulator of mitochondrial transcription elongation in vitro. | 53 |
| 25635099 | 2015 | Mitochondrial biology. Replication-transcription switch in human mitochondria. | 87 |
| 25690892 | 2015 | TEFM is a potent stimulator of mitochondrial transcription elongation in vitro. | 53 |
| 21278163 | 2011 | TEFM (c17orf42) is necessary for transcription of human mtDNA. | 93 |
| 21278163 | 2011 | TEFM (c17orf42) is necessary for transcription of human mtDNA. | 93 |
| 19291764 | 2009 | RNF135 mutations are not present in patients with Sotos syndrome-like features. | 4 |
| 19291764 | 2009 | RNF135 mutations are not present in patients with Sotos syndrome-like features. | 4 |
Citation
Dessen P
TEFM (transcription elongation factor, mitochondrial)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74613/tefm-(transcription-elongation-factor-mitochondrial)
