Identity
HGNC
LOCATION
Xq25
LOCUSID
ALIAS
CXorf3,MRX12,MRX35,THO2,dJ506G2.1,hTREX120
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57187
MIM: 300395
HGNC: 19073
Ensembl: ENSG00000125676
Variants:
dbSNP: 57187
ClinVar: 57187
TCGA: ENSG00000125676
COSMIC: THOC2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31680623 | 2019 | Knockdown THOC2 suppresses the proliferation and invasion of melanoma. | 14 |
| 31680623 | 2019 | Knockdown THOC2 suppresses the proliferation and invasion of melanoma. | 14 |
| 29851191 | 2018 | Severe neurocognitive and growth disorders due to variation in THOC2, an essential component of nuclear mRNA export machinery. | 12 |
| 29851191 | 2018 | Severe neurocognitive and growth disorders due to variation in THOC2, an essential component of nuclear mRNA export machinery. | 12 |
| 26166480 | 2015 | THOC2 Mutations Implicate mRNA-Export Pathway in X-Linked Intellectual Disability. | 32 |
| 26166480 | 2015 | THOC2 Mutations Implicate mRNA-Export Pathway in X-Linked Intellectual Disability. | 32 |
| 15998806 | 2005 | Recruitment of the human TREX complex to mRNA during splicing. | 233 |
| 15998806 | 2005 | Recruitment of the human TREX complex to mRNA during splicing. | 233 |
Citation
Dessen P
THOC2 (THO complex 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74679/thoc2-(tho-complex-2)
