Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29928
MIM: 607251
HGNC: 17317
Ensembl: ENSG00000177370
Variants:
dbSNP: 29928
ClinVar: 29928
TCGA: ENSG00000177370
COSMIC: TIMM22
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000177370 | ENST00000327158 | Q9Y584 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Mitochondrial protein import | REACTOME | R-HSA-1268020 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38294104 | 2024 | TIM22 and TIM29 inhibit HBV replication by up-regulating SRSF1 expression. | 1 |
| 38294104 | 2024 | TIM22 and TIM29 inhibit HBV replication by up-regulating SRSF1 expression. | 1 |
| 32901109 | 2021 | Cryo-EM structure of the human mitochondrial translocase TIM22 complex. | 28 |
| 33125709 | 2021 | Defining the architecture of the human TIM22 complex by chemical crosslinking. | 5 |
| 33476211 | 2021 | The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism. | 13 |
| 32901109 | 2021 | Cryo-EM structure of the human mitochondrial translocase TIM22 complex. | 28 |
| 33125709 | 2021 | Defining the architecture of the human TIM22 complex by chemical crosslinking. | 5 |
| 33476211 | 2021 | The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism. | 13 |
| 32142709 | 2020 | Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos. | 13 |
| 32645990 | 2020 | Biogenesis of Mitochondrial Metabolite Carriers. | 17 |
| 32142709 | 2020 | Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos. | 13 |
| 32645990 | 2020 | Biogenesis of Mitochondrial Metabolite Carriers. | 17 |
| 31103774 | 2019 | A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria. | 25 |
| 31103774 | 2019 | A MICOS-TIM22 Association Promotes Carrier Import into Human Mitochondria. | 25 |
| 28712724 | 2017 | Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. | 57 |
Citation
Dessen P
TIMM22 (translocase of inner mitochondrial membrane 22)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74705/timm22-(translocase-of-inner-mitochondrial-membrane-22)
