Identity
HGNC
LOCATION
9q21.13
LOCUSID
ALIAS
DFNA36,DFNB11,DFNB7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 117531
MIM: 606706
HGNC: 16513
Ensembl: ENSG00000165091
Variants:
dbSNP: 117531
ClinVar: 117531
TCGA: ENSG00000165091
COSMIC: TMC1
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38066485 | 2023 | Novel autosomal dominant TMC1 variants linked to hearing loss: insight into protein-lipid interactions. | 2 |
| 38066485 | 2023 | Novel autosomal dominant TMC1 variants linked to hearing loss: insight into protein-lipid interactions. | 2 |
| 34523024 | 2022 | Prevalence and clinical features of autosomal dominant and recessive TMC1-associated hearing loss. | 7 |
| 35089886 | 2022 | A novel splicing variant in the TMC1 gene causes non-syndromic hearing loss in a Chinese family. | 2 |
| 36542715 | 2022 | GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans. | 4 |
| 34523024 | 2022 | Prevalence and clinical features of autosomal dominant and recessive TMC1-associated hearing loss. | 7 |
| 35089886 | 2022 | A novel splicing variant in the TMC1 gene causes non-syndromic hearing loss in a Chinese family. | 2 |
| 36542715 | 2022 | GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans. | 4 |
| 33824189 | 2021 | New Tmc1 Deafness Mutations Impact Mechanotransduction in Auditory Hair Cells. | 15 |
| 33824189 | 2021 | New Tmc1 Deafness Mutations Impact Mechanotransduction in Auditory Hair Cells. | 15 |
| 31854501 | 2020 | Identification of TMC1 as a relatively common cause for nonsyndromic hearing loss in the Saudi population. | 10 |
| 32802042 | 2020 | Compound Heterozygous Mutations in TMC1 and MYO15A Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss in Two Chinese Han Families. | 2 |
| 33168709 | 2020 | Deafness mutation D572N of TMC1 destabilizes TMC1 expression by disrupting LHFPL5 binding. | 18 |
| 33205915 | 2020 | Novel homozygous variants in the TMC1 and CDH23 genes cause autosomal recessive nonsyndromic hearing loss. | 3 |
| 31854501 | 2020 | Identification of TMC1 as a relatively common cause for nonsyndromic hearing loss in the Saudi population. | 10 |
Citation
Dessen P
TMC1 (transmembrane channel like 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/74743/tmc1-(transmembrane-channel-like-1)
