TMEM130 (transmembrane protein 130)

2014-11-01  

Identity

HGNC
TMEM130
LOCATION
7q22.1
LOCUSID
222865
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 222865
HGNC: 25429
Ensembl: ENSG00000166448

Variants:

dbSNP: 222865
ClinVar: 222865
TCGA: ENSG00000166448
COSMIC: TMEM130

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166448ENST00000339375Q8N3G9
ENSG00000166448ENST00000345589Q8N3G9
ENSG00000166448ENST00000416379Q8N3G9
ENSG00000166448ENST00000445790C9JQV5
ENSG00000166448ENST00000450876G3V0E7

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
341625082022The promoter aberrant methylation status of TMEM130 is associated with gastric cancer.1
341625082022The promoter aberrant methylation status of TMEM130 is associated with gastric cancer.1
342078492021Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins.1
347631162021DNA methylation-mediated down-regulation of TMEM130 promotes cell migration in breast cancer.4
342078492021Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins.1
347631162021DNA methylation-mediated down-regulation of TMEM130 promotes cell migration in breast cancer.4

Citation

Dessen P

TMEM130 (transmembrane protein 130)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74791/tmem130-(transmembrane-protein-130)