Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 143872
MIM: 615936
HGNC: 26545
Ensembl: ENSG00000165895
Variants:
dbSNP: 143872
ClinVar: 143872
TCGA: ENSG00000165895
COSMIC: ARHGAP42
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32710738 | 2021 | Maternal Hypertension-Related Genotypes and Congenital Heart Defects. | 0 |
| 34232960 | 2021 | A homozygous stop-gain variant in ARHGAP42 is associated with childhood interstitial lung disease, systemic hypertension, and immunological findings. | 1 |
| 32710738 | 2021 | Maternal Hypertension-Related Genotypes and Congenital Heart Defects. | 0 |
| 34232960 | 2021 | A homozygous stop-gain variant in ARHGAP42 is associated with childhood interstitial lung disease, systemic hypertension, and immunological findings. | 1 |
| 29099324 | 2020 | GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure. | 6 |
| 31886719 | 2020 | Transcriptional and posttranscriptional regulation of the SMC-selective blood pressure-associated gene, ARHGAP42. | 4 |
| 29099324 | 2020 | GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure. | 6 |
| 31886719 | 2020 | Transcriptional and posttranscriptional regulation of the SMC-selective blood pressure-associated gene, ARHGAP42. | 4 |
| 30903111 | 2019 | Haploinsufficiency of ARHGAP42 is associated with hypertension. | 10 |
| 30903111 | 2019 | Haploinsufficiency of ARHGAP42 is associated with hypertension. | 10 |
| 28112683 | 2017 | Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. | 24 |
| 28112683 | 2017 | Blood pressure-associated polymorphism controls ARHGAP42 expression via serum response factor DNA binding. | 24 |
| 24335996 | 2013 | The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension. | 33 |
| 24335996 | 2013 | The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension. | 33 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
ARHGAP42 (Rho GTPase activating protein 42)
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/gene/74797/haematological-explorer/meetings/
