TMEM41B (transmembrane protein 41B)

2014-11-01  

Identity

HGNC
TMEM41B
LOCATION
11p15.4
LOCUSID
440026
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 440026
HGNC: 28948
Ensembl: ENSG00000166471

Variants:

dbSNP: 440026
ClinVar: 440026
TCGA: ENSG00000166471
COSMIC: TMEM41B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166471ENST00000299596Q5BJD5
ENSG00000166471ENST00000524543Q5BJD5
ENSG00000166471ENST00000527813E9PJ42
ENSG00000166471ENST00000528080Q5BJD5
ENSG00000166471ENST00000533723Q5BJD5
ENSG00000166471ENST00000611268Q5BJD5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
355363182022VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection.22
355363182022VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection.22
333384212021TMEM41B Is a Pan-flavivirus Host Factor.97
340437402021TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.32
333384212021TMEM41B Is a Pan-flavivirus Host Factor.97
340437402021TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.32
309339662019CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor.74
309339662019CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor.74
300934942018Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation.106
301269242018TMEM41B is a novel regulator of autophagy and lipid mobilization.79
300934942018Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation.106
301269242018TMEM41B is a novel regulator of autophagy and lipid mobilization.79

Citation

Dessen P

TMEM41B (transmembrane protein 41B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74943/tmem41b-(transmembrane-protein-41b)