TMPRSS13 (transmembrane serine protease 13)

2014-11-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
MSP,MSPL,MSPS,TMPRSS11

Other Information

Locus ID:

NCBI: 84000
MIM: 610050
HGNC: 29808
Ensembl: ENSG00000137747

Variants:

dbSNP: 84000
ClinVar: 84000
TCGA: ENSG00000137747
COSMIC: TMPRSS13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137747ENST00000430170Q9BYE2
ENSG00000137747ENST00000445164Q9BYE2
ENSG00000137747ENST00000524993Q9BYE2
ENSG00000137747ENST00000526090Q9BYE2
ENSG00000137747ENST00000528135E9PR79
ENSG00000137747ENST00000528626Q9BYE2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Influenza AKEGGko05164
Influenza AKEGGhsa05164

References

Pubmed IDYearTitleCitations
361319182022IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike.1
361319182022IL4I1 binds to TMPRSS13 and competes with SARS-CoV-2 spike.1
336710762021TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.42
338208272021Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza.5
345624512021Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization.7
336710762021TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.42
338208272021Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza.5
345624512021Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization.7
328078082020TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer.8
328688772020The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy.11
328078082020TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer.8
328688772020The cell-surface anchored serine protease TMPRSS13 promotes breast cancer progression and resistance to chemotherapy.11
287102772017Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.18
287102772017Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.18
251228022014DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.54

Citation

Dessen P

TMPRSS13 (transmembrane serine protease 13)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75014/tmprss13-(transmembrane-serine-protease-13)