Identity
HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
CGI-31,NEDMCMS,PDIA12,PIG26,TXNDC14
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51075
MIM: 616715
HGNC: 30739
Ensembl: ENSG00000213593
Variants:
dbSNP: 51075
ClinVar: 51075
TCGA: ENSG00000213593
COSMIC: TMX2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | 32451486 | |
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD | 32451486 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38147024 | 2023 | TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer. | 0 |
| 38147024 | 2023 | TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer. | 0 |
| 31586943 | 2020 | Recurrent homozygous damaging mutation in TMX2, encoding a protein disulfide isomerase, in four families with microlissencephaly. | 4 |
| 31586943 | 2020 | Recurrent homozygous damaging mutation in TMX2, encoding a protein disulfide isomerase, in four families with microlissencephaly. | 4 |
| 31653923 | 2019 | Thioredoxin-related transmembrane protein 2 (TMX2) regulates the Ran protein gradient and importin-β-dependent nuclear cargo transport. | 3 |
| 31735293 | 2019 | TMX2 Is a Crucial Regulator of Cellular Redox State, and Its Dysfunction Causes Severe Brain Developmental Abnormalities. | 19 |
| 31653923 | 2019 | Thioredoxin-related transmembrane protein 2 (TMX2) regulates the Ran protein gradient and importin-β-dependent nuclear cargo transport. | 3 |
| 31735293 | 2019 | TMX2 Is a Crucial Regulator of Cellular Redox State, and Its Dysfunction Causes Severe Brain Developmental Abnormalities. | 19 |
| 22045338 | 2012 | Palmitoylated TMX and calnexin target to the mitochondria-associated membrane. | 108 |
| 22045338 | 2012 | Palmitoylated TMX and calnexin target to the mitochondria-associated membrane. | 108 |
| 12670024 | 2003 | Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2. | 13 |
| 12670024 | 2003 | Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2. | 13 |
Citation
Dessen P
TMX2 (thioredoxin related transmembrane protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75028/tmx2-(thioredoxin-related-transmembrane-protein-2)
