Identity
HGNC
LOCATION
1p34.1
LOCUSID
ALIAS
PCH7,TOE-1,hCaf1z
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 114034
MIM: 613931
HGNC: 15954
Ensembl: ENSG00000132773
Variants:
dbSNP: 114034
ClinVar: 114034
TCGA: ENSG00000132773
COSMIC: TOE1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132773 | ENST00000372090 | Q96GM8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36738896 | 2023 | Novel compound heterozygous missense variants in TOE1 gene associated with pontocerebellar hypoplasia type 7. | 2 |
| 37635087 | 2023 | Genetic and prenatal diagnosis of a Chinese pedigree with pathogenic TOE1 variants causing pontocerebellar hypoplasia type 7. | 0 |
| 36738896 | 2023 | Novel compound heterozygous missense variants in TOE1 gene associated with pontocerebellar hypoplasia type 7. | 2 |
| 37635087 | 2023 | Genetic and prenatal diagnosis of a Chinese pedigree with pathogenic TOE1 variants causing pontocerebellar hypoplasia type 7. | 0 |
| 30371886 | 2019 | TOE1 acts as a 3' exonuclease for telomerase RNA and regulates telomere maintenance. | 28 |
| 30371886 | 2019 | TOE1 acts as a 3' exonuclease for telomerase RNA and regulates telomere maintenance. | 28 |
| 29669292 | 2018 | PARN and TOE1 Constitute a 3' End Maturation Module for Nuclear Non-coding RNAs. | 41 |
| 29669292 | 2018 | PARN and TOE1 Constitute a 3' End Maturation Module for Nuclear Non-coding RNAs. | 41 |
| 28092684 | 2017 | Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. | 43 |
| 28092684 | 2017 | Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. | 43 |
| 26056259 | 2015 | TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability. | 12 |
| 26056259 | 2015 | TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability. | 12 |
| 12562764 | 2003 | In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1. | 12 |
| 12562764 | 2003 | In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1. | 12 |
Citation
Dessen P
TOE1 (target of EGR1, exonuclease)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75047/gene-fusions/tumors-explorer/
