TOMM5 (translocase of outer mitochondrial membrane 5)

2014-11-01  

Identity

HGNC
TOMM5
LOCATION
9p13.2
LOCUSID
401505
ALIAS
C9orf105,Tom5,bA613M10.3

Other Information

Locus ID:

NCBI: 401505
MIM: 616169
HGNC: 31369
Ensembl: ENSG00000175768

Variants:

dbSNP: 401505
ClinVar: 401505
TCGA: ENSG00000175768
COSMIC: TOMM5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175768ENST00000321301Q8N4H5
ENSG00000175768ENST00000377773Q8N4H5
ENSG00000175768ENST00000401811F8W8Z9
ENSG00000175768ENST00000540941H0YFG9
ENSG00000175768ENST00000544379Q8N4H5

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Mitochondrial protein importREACTOMER-HSA-1268020
MitophagyREACTOMER-HSA-5205647
Pink/Parkin Mediated MitophagyREACTOMER-HSA-5205685

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
183318222008Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane.24
183318222008Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane.24

Citation

Dessen P

TOMM5 (translocase of outer mitochondrial membrane 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75053/tomm5-(translocase-of-outer-mitochondrial-membrane-5)