Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64499
MIM: 191081
HGNC: 14120
Ensembl: ENSG00000197253
Variants:
dbSNP: 64499
ClinVar: 64499
TCGA: ENSG00000197253
COSMIC: TPSB2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000197253 | ENST00000606293 | P20231 |
| ENSG00000197253 | ENST00000606293 | A0A140VJT7 |
| ENSG00000197253 | ENST00000611196 | A0A087X1U0 |
| ENSG00000197253 | ENST00000612142 | A0A087WUI4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37511292 | 2023 | Increase in TPSB2 and TPSD1 Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight. | 2 |
| 37511292 | 2023 | Increase in TPSB2 and TPSD1 Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight. | 2 |
| 31337736 | 2019 | Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia. | 32 |
| 31337736 | 2019 | Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia. | 32 |
| 24142694 | 2013 | Allosteric control of βII-tryptase by a redox active disulfide bond. | 13 |
| 24142694 | 2013 | Allosteric control of βII-tryptase by a redox active disulfide bond. | 13 |
| 19748655 | 2009 | Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. | 23 |
| 19748655 | 2009 | Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. | 23 |
| 19748655 | 2009 | Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. | 23 |
| 19748655 | 2009 | Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. | 23 |
| 17449330 | 2007 | Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels. | 12 |
| 17449330 | 2007 | Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels. | 12 |
| 15567416 | 2005 | Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase. | 15 |
| 15567416 | 2005 | Structural requirements and mechanism for heparin-dependent activation and tetramerization of human betaI- and betaII-tryptase. | 15 |
Citation
Dessen P
TPSB2 (tryptase beta 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75086/tpsb2-(tryptase-beta-2)
