Identity
HGNC
LOCATION
2q33.1
LOCUSID
ALIAS
ALS2CR3,CALS-C,GRIF-1,GRIF1,MILT2,OIP98
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 66008
MIM: 607334
HGNC: 13206
Ensembl: ENSG00000115993
Variants:
dbSNP: 66008
ClinVar: 66008
TCGA: ENSG00000115993
COSMIC: TRAK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115993 | ENST00000332624 | O60296 |
| ENSG00000115993 | ENST00000430254 | O60296 |
| ENSG00000115993 | ENST00000440597 | Q53RS6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolic pathways | KEGG | hsa01100 |
| GABAergic synapse | KEGG | ko04727 |
| GABAergic synapse | KEGG | hsa04727 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34321481 | 2021 | Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors. | 46 |
| 34321481 | 2021 | Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors. | 46 |
| 32267991 | 2020 | miR-487b and TRAK2 that form an axis to regulate the aggressiveness of osteosarcoma, are potential therapeutic targets and prognostic biomarkers. | 3 |
| 32267991 | 2020 | miR-487b and TRAK2 that form an axis to regulate the aggressiveness of osteosarcoma, are potential therapeutic targets and prognostic biomarkers. | 3 |
| 28655204 | 2017 | TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis. | 13 |
| 28655204 | 2017 | TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis. | 13 |
| 26658612 | 2016 | APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane. | 24 |
| 26658612 | 2016 | APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane. | 24 |
| 25653102 | 2015 | Localization of the kinesin adaptor proteins trafficking kinesin proteins 1 and 2 in primary cultures of hippocampal pyramidal and cortical neurons. | 15 |
| 25653102 | 2015 | Localization of the kinesin adaptor proteins trafficking kinesin proteins 1 and 2 in primary cultures of hippocampal pyramidal and cortical neurons. | 15 |
| 23395375 | 2013 | TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. | 197 |
| 23395375 | 2013 | TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites. | 197 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19103291 | 2009 | GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons. | 89 |
Citation
Dessen P
TRAK2 (trafficking kinesin protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75103/trak2-(trafficking-kinesin-protein-2)
