TRAPPC8 (trafficking protein particle complex subunit 8)

2014-11-01  

Identity

HGNC
TRAPPC8
LOCATION
18q12.1
LOCUSID
22878
ALIAS
GSG1,HsT2706,KIAA1012,TRS85
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22878
MIM: 614136
HGNC: 29169
Ensembl: ENSG00000153339

Variants:

dbSNP: 22878
ClinVar: 22878
TCGA: ENSG00000153339
COSMIC: TRAPPC8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153339ENST00000283351Q9Y2L5
ENSG00000153339ENST00000578658J3QR00
ENSG00000153339ENST00000580104J3KSL8
ENSG00000153339ENST00000581057J3QQS5
ENSG00000153339ENST00000582513J3QSA1
ENSG00000153339ENST00000582539J3QQJ5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
267111782016TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic.93
267111782016TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic.93
218580812011The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability.36
218580812011The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability.36

Citation

Dessen P

TRAPPC8 (trafficking protein particle complex subunit 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75117/trappc8-(trafficking-protein-particle-complex-subunit-8)