Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 285852
MIM: 614664
HGNC: 30807
Ensembl: ENSG00000188056
Variants:
dbSNP: 285852
ClinVar: 285852
TCGA: ENSG00000188056
COSMIC: TREML4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188056 | ENST00000341495 | Q6UXN2 |
| ENSG00000188056 | ENST00000448827 | Q6UXN2 |
| ENSG00000188056 | ENST00000461240 | H7C4X5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10066 | duloxetine | Chemical | ClinicalAnnotation | associated | PD | 29407288 | |
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | 29407288 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36329152 | 2022 | TREML4 polymorphisms increase the mRNA in blood leukocytes in the progression of atherosclerosis. | 0 |
| 36329152 | 2022 | TREML4 polymorphisms increase the mRNA in blood leukocytes in the progression of atherosclerosis. | 0 |
| 32292401 | 2020 | TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse. | 12 |
| 32292401 | 2020 | TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse. | 12 |
| 31076644 | 2019 | TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease. | 5 |
| 31076644 | 2019 | TREML4 mRNA Expression and Polymorphisms in Blood Leukocytes are Associated with Atherosclerotic Lesion Extension in Coronary Artery Disease. | 5 |
| 24975946 | 2014 | Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification. | 19 |
| 24975946 | 2014 | Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification. | 19 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
Citation
Dessen P
TREML4 (triggering receptor expressed on myeloid cells like 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/75135/treml4-(triggering-receptor-expressed-on-myeloid-cells-like-4)
